Pregnant? Commit to Healthy Choices to Reduce The Risk Of Birth Defects

It is a happy and blessed thing to be parents. As parents, we hope to see our children live healthily and enjoy happiness when born into this world. Therefore, it is very common for parents to worry about maternal health and fetal health during pregnancy. Some of the common worries include the baby’s health and the ability to be a good parent and complications during childbirth. It would be heartbreaking news if our children happened to have some disorder. However, due to the advancement of medicine and science, there are some known risk factors and screening tests to help parents detect the disorders as early as possible. Other than that, parents should also be aware if they have a high risk of giving birth to a child with special needs disorders so that they can try to minimise their risk through lifestyle modification and regular check-ups.

Today we will introduce you to scientifically proven risk factors and ways to reduce the risk.

Possible Prenatal Factors Related To Special Needs Children 

These are the common developmental disorders and some of their prenatal risk factors. The details of these risk factors will be discussed in the future article.

Autism Spectrum Disorder (ASD)Attention Deficit Hyperactivity Disorder (ADHD)Down SyndromeCerebral Palsy
Advanced Maternal And Paternal Age≥35 Years.In-utero Exposure To Maternal StressAdvanced Maternal AgeInfections
Gestational HypertensionAlcohol DrinkingWestern Dietary Patterns (processed foods, red meat, sugar).Mother‘s Systemic Diseases. 
Gestational DiabetesCigarette SmokingCigarette SmokingMother Has Immune. Disorder
Threatened AbortionPrescribed Drugs (e.g., paracetamol), AndIllicit SubstancesAbnormal Folate Metabolism In Mother; Lower take Of Folate In FatherMultiple Pregnancy
Antepartum HaemorrhageEnvironmental ToxinsEnvironmental Exposure To Pyrethroid InsecticidesDrugs And Stimulants Used

Ways Might Reduce The Possibility Of Giving Birth To A Special Needs Child

1. Eat healthy

Mothers’ excessive weight gain or nutritional deficiency will directly affect their children’s growth and health. Women’s weight gain recommendations should be individualized to reduce the risk of obesity and chronic diseases for the child and mother.

  • The Institute of Medicine has developed guidelines for optimal weight gain during pregnancy.
BMIOptimal weight gain (kg)
<19Slightly more than 11.5-16
19.8-2611.5-16
>265.9–11.5
  • Here are listed nutrients’ references to intake for pregnant women aged 19–30 years. 
NutrientAmount
Energy(kcal/day)2855
Carbohydrate(g/day)175
Total fiber(g/day)28
Protein (g/day)71
N-6 PUFA (g/day)13
N-3 PUFA (g/day)1.4
Calcium(mg/day)1100
Fluoride(mg/day)3
Phosphorus (mg/day)700
Chromium (mcg/day)30
Cooper(mcg/day)1000
Iodine(mcg/day)220
Iron (mg/day)27
Magnesium  (mg/day)350
Manganese  (mg/day)2
Molybdenum (mcg/day)50
Selenium(mcg/day)60
Zinc  (mg/day)11
Choline (mg/day)450
Folate(mcg/day)600
Niacin (mg/day)18
Pantothenic acid(mg/day)6
Riboflavin (mg/day)1.4
Thiamin(mg/day)1.4
Vitamin A (mcg/day)770
Vitamin B12(mcg/day)2.6
Vitamin B6(mg/day)1.9
Vitamin C(mg/day)85
Biotin (mcg/day)30
Vitamin D (mcg/day)5
VItamin E(mg/day)15
Vitamin K (mcg/day)90
Water (l/day)3
Chloride (g/day)2.3
Potassium(g/day)4.7
Sodium(g/day)1.5
  • An example of a diet for a pregnant woman eating 2800kCal/day
Food group 2800kCal/day
Fruits2.5 cups
Vegetables3.5 cups
Dark green3 cups/week
Orange2.5 cups/week
Legumes 3.5 cups/week
Starchy7 cups/week
Other8.5 cups/week
Grains10-oz
Whole5
Enriched5
Meat and Beans7-oz
Milk3 cups
Oils36g
Discretionary calorie allowance: Excessive calories to enjoy after meeting the above nutrient requirements462kCal/day

2. Exercise Regularly

Pregnant women who do physical exercise regularly can significantly reduce their risk of obesity and comorbidities such as gestational diabetes, gestational hypertension, and other prenatal complications.  

  • Here are the physical activity guidelines for pregnant women from the American College of Obstetricians and Gynecologists, 2020.
Safe physical activities during pregnancyUnsafe physical activities during pregnancy
Walkingcontact activities with a high risk of abdominal trauma or imbalance.
Stationary cyclingScuba diving
Aerobic exercise
Dancing
Resistance exercises using weights or elastic bands
Stretching exercises
Hydrotherapy or water aerobics

3. Maintain good sleep quality 

A good sleep quality can help a pregnant woman achieve better physical and psychological health. However, studies show that there is an association between pregnancy and sleeping problems; for example, one cannot fall asleep or cannot maintain sleep. The medical associations have not developed guidelines for sleep in pregnant women. Here we are going to share some medical experts’ opinions on sleep.

  • Sleeping position: Medical experts recommend pregnant women lie on their left side while sleeping to prevent the body from pushing too hard on their liver.
  • Sleeping duration: Between 7-9 hours 
  • Sleeping timing: no consensus

Look for counseling and psychological professionals if mothers are feeling stressed.

  • Follow up in the Obstetrics and Gynaecology Clinic Checkup on time, and here are listed some prenatal screening and assessments for pregnant mothers.
DisordersTimingPrenatal tests for special-needs disorders
Autism Spectrum Disorder (ASD)As early as week 9Prenatal genetic testing (PGT)
 Week 14 to week 27Prenatal ultrasound
Attention deficit hyperactivity disorder (ADHD)nilCurrently, we do not have any prenatal tests for detecting ADHD in infants.
Down syndromeAs early as week 10Cell-free fetal DNA testing
PAPP+ beta-hCG:Week 11 to week 13 NT: Week 10 to Week 13First trimester combined test(including nuchal translucency(NT), pregnancy-associated plasma protein(PAPP) and free/intact/total human chorionic gonadotropin (beta-hCG))
Week 15 to week 18Quadruple test
Draw blood two times. First time at week 11 to 13NT: Week 11 to 13Second time at week 15 to week 18Integrated or Sequential test (it is a combination of the first trimester combined test and the quadruple test).
Draw blood two times. First time at week 11 to 13Second time at week 15 to week 18Serum integrated test(it is an integrated or sequential test without NT)
Week 10 to week 12Chorionic villus sampling
Week 15 to week 20Amniocentesis
Absent nasal bone and an abnormally huge bladder can be detected from week 10 to week 14.Ultrasound
Cerebal palsyOnly if the fetus is in a high-risk group for developing cerebral palsy can be detected.Ultrasound

Reminder To Parents

It is still unclear whether these factors are causal or play a secondary role in the development of special-needs disorders. Furthermore, no matter the accuracy and the accessibility of the medical tests and imaging studies, medicine still has numerous inevitable limitations in detecting special-needs disorders. Medical professionals and parents with multiple risk factors should closely monitor the development of their offspring, and a comprehensive assessment should be conducted when the fetus is highly suspicious of special-needs disorders. Every life born into this world is equal, no matter if they have special-needs disorders or not. They should enjoy the right to be loved and cherished by humanity.

References:

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